Carcinomatous Meningitis from Unknown Primary Carcinoma
نویسندگان
چکیده
منابع مشابه
Carcinomatous Meningitis from Unknown Primary Carcinoma
Carcinomatous meningitis (CM) occurs in 3 to 8% of cancer patients. Patients present with a focal symptom, and multifocal signs are often found following neurological examination. The gold standard for diagnosis remains the demonstration of carcinomatous cells in the cerebrospinal fluid on cytopathological examination. Despite the poor prognosis, palliative treatment could improve quality of li...
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Neoplastic meningitis, also known as carcinomatous meningitis, reflects the metastatic infiltration of the cerebrospinal fluid (CSF) and leptomeninges (pia and arachnoid) by cancer. It is the is the third most common cause of central nervous system (CNS) metastases after brain metastases and epidural spinal cord compression [1]. Leptomeningeal metastasis (LMM) is a devastating complication of m...
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Treatment options include whole-brain irradiation, systemic chemotherapy, and intrathecal chemotherapy such as methotrexate [2]. Despite these measures, the prognosis is poor with a median survival of 2–3 months, and focal neurologic dysfunctions do not improve in most cases [1]. The benefit of EGFR tyrosine kinase inhibitors (TKIs) in the treatment of carcinomatous meningitis in patients with ...
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Carcinomatous meningitis is a rare clinical entity associated with gynaecological malignancies. However, it is an unusual occurrence in carcinoma of uterine cervix. Here we report a case of a 55-year-old female who was diagnosed to have carcinoma of uterine cervix stage IIB and was started on radiotherapy to whole pelvis with curative intent. One week later she complained of sudden onset of hea...
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Meningeal metastasis is rare in the clinical course of ovarian carcinoma and its prognosis is extremely poor. We experienced a case of carcinomatous meningitis from metastatic ovarian small cell carcinoma. A 33-year-old woman with atypical genital bleeding, was diagnosed with a right ovarian tumor and referred to our department. She underwent a total abdominal hysterectomy, bilateral salpingo-o...
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ژورنال
عنوان ژورنال: Case Reports in Oncology
سال: 2009
ISSN: 1662-6575
DOI: 10.1159/000241985